ADCY10 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human spleen with ADCY10 polyclonal antibody (Cat # PAB20803) shows strong cytoplasmic positivity in cells of red pulp at 1:50-1:200 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ADCY10.
Immunogen
Recombinant protein corresponding to amino acids of human ADCY10.
Sequence
NLENLVAQNTTGPVFCPRLYHLMAYVCILMGDGQKCGLFLNTALRLSETQGNILEKCWLNMNKESWYSTSELKEDQWLQTILSLPSW
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human spleen with ADCY10 polyclonal antibody (Cat # PAB20803) shows strong cytoplasmic positivity in cells of red pulp at 1:50-1:200 dilution. -
Gene Info — ADCY10
Entrez GeneID
55811Protein Accession#
Q96PN6Gene Name
ADCY10
Gene Alias
HCA2, RP1-313L4.2, SAC, SACI, Sacy
Gene Description
adenylate cyclase 10 (soluble)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. [provided by RefSeq
Other Designations
3',5'-cyclic AMP synthetase|AH-related protein|ATP pyrophosphate-lyase|Hypercalciuria, absorptive, 2|OTTHUMP00000032525|soluble adenylyl cyclase|testicular soluble adenylyl cyclase (SAC)
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Pathway
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Disease
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