PTPRZ1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PTPRZ1.
Immunogen
Recombinant protein corresponding to amino acids of human PTPRZ1.
Sequence
LFRHLHTVSQILPQVTSATESDKVPLHASLPVAGGDLLLEPSLAQYSDVLSTTHAASETLEFGSESGVLYKTLMFSQVEPPSSDAMMHARSSGPEPSYALSDNEGSQHIFTVSYSSAIPVHDSVGVTYQGSLFSGPSHIPIPKSSLIT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebral cortex with PTPRZ1 polyclonal antibody (Cat # PAB20795) shows cytoplasmic positivity in neuronal cells. -
Gene Info — PTPRZ1
Entrez GeneID
5803Protein Accession#
P23471Gene Name
PTPRZ1
Gene Alias
HPTPZ, HPTPzeta, PTP-ZETA, PTP18, PTPRZ, PTPZ, RPTPB, RPTPbeta, phosphacan
Gene Description
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
Gene Ontology
HyperlinkGene Summary
This gene is a member of the receptor type protein tyrosine phosphatase family and encodes a single-pass type I membrane protein with two cytoplasmic tyrosine-protein phosphatase domains, an alpha-carbonic anhydrase domain and a fibronectin type-III domain. Expression of this gene is induced in gastric cancer cells, in the remyelinating oligodendrocytes of multiple sclerosis lesions, and in human embryonic kidney cells under hypoxic conditions. Both the protein and transcript are overexpressed in glioblastoma cells, promoting their haptotactic migration. Alternative splice variants that encode different protein isoforms have been described but their full-length nature has not been determined. [provided by RefSeq
Other Designations
protein tyrosine phosphatase, receptor-type, zeta polypeptide 1|protein tyrosine phosphatase, receptor-type, zeta1|receptor-type tyrosine phosphatase beta/zeta
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Interactome
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