GJC3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant GJC3.
Immunogen
Recombinant protein corresponding to amino acids of human GJC3.
Sequence
RTWKHKSSSSKYFLTSESTRRHKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with GJC3 polyclonal antibody (Cat # PAB20786) shows strong cytoplasmic positivity in purkinje cells at 1:20-1:50 dilution. -
Gene Info — GJC3
Entrez GeneID
349149Protein Accession#
Q8NFK1Gene Name
GJC3
Gene Alias
CX30.2, CX31.3, Cx29, GJE1
Gene Description
gap junction protein, gamma 3, 30.2kDa
Gene Ontology
HyperlinkGene Summary
Connexins, such as GJC3, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM
Other Designations
connexin 29|connexin 30.2|connexin 31.3|gap junction protein, epsilon 1, 29kDa
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Interactome
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Disease
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