KCNE3 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with KCNE3 polyclonal antibody (Cat # PAB20775) shows strong cytoplasmic positivity in granular pattern in tubular cells at 1:500-1:1000 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant KCNE3.
Immunogen
Recombinant protein corresponding to amino acids of human KCNE3.
Sequence
METTNGTETWYESLHAVLKALNATLHSNLLCRPGPGLGPDNQTEERRASLPGRDDN
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with KCNE3 polyclonal antibody (Cat # PAB20775) shows strong cytoplasmic positivity in granular pattern in tubular cells at 1:500-1:1000 dilution. -
Gene Info — KCNE3
Entrez GeneID
10008Protein Accession#
Q9Y6H6Gene Name
KCNE3
Gene Alias
DKFZp781H21101, HOKPP, MGC102685, MGC129924, MiRP2
Gene Description
potassium voltage-gated channel, Isk-related family, member 3
Gene Ontology
HyperlinkGene Summary
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq
Other Designations
cardiac voltage-gated potassium channel accessory subunit|minK-related peptide 2|minimum potassium ion channel-related peptide 2|potassium voltage-gated channel subfamily E member 3|voltage-gated K+ channel subunit MIRP2
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Interactome
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Disease
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