KCNC4 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant KCNC4.
Immunogen
Recombinant protein corresponding to amino acids of human KCNC4.
Sequence
ISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human adrenal gland with KCNC4 polyclonal antibody (Cat # PAB20762) shows strong cytoplasmic positivity in cortical cells at 1:50-1:200 dilution. -
Gene Info — KCNC4
Entrez GeneID
3749Protein Accession#
Q03721Gene Name
KCNC4
Gene Alias
HKSHIIIC, KSHIIIC, KV3.4, MGC126818
Gene Description
potassium voltage-gated channel, Shaw-related subfamily, member 4
Omim ID
176265Gene Ontology
HyperlinkGene Summary
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Shaw-related voltage-gated potassium channel protein 4|potassium voltage-gated channel subfamily C member 4|voltage-gated potassium channel subunit KV3.4
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