DPM3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant DPM3.
Immunogen
Recombinant protein corresponding to amino acids of human DPM3.
Sequence
FHDCEDAARELQSQIQEARADLARR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with DPM3 polyclonal antibody (Cat # PAB20750).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human stomach with DPM3 polyclonal antibody (Cat # PAB20750) shows strong cytoplasmic positivity in glandular cells. -
Gene Info — DPM3
Entrez GeneID
54344Protein Accession#
Q9P2X0Gene Name
DPM3
Gene Alias
MGC125904, MGC125905, MGC34275
Gene Description
dolichyl-phosphate mannosyltransferase polypeptide 3
Omim ID
605951Gene Ontology
HyperlinkGene Summary
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex. [provided by RefSeq
Other Designations
OTTHUMP00000033283|OTTHUMP00000033284|OTTHUMP00000033285|dolichol-phosphate mannose synthase subunit 3|dolichyl-phosphate beta-D-mannosyltransferase subunit 3|mannose-P-dolichol synthase subunit 3|prostin 1
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Interactome
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Pathway
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