SPTBN1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with SPTBN1 polyclonal antibody (Cat # PAB20642) shows strong cytoplasmic and membranous positivity in cells in tubules and cells in glomeruli.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant SPTBN1.
Immunogen
Recombinant protein corresponding to amino acids of human SPTBN1.
Sequence
SLLHQFQADADDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRPTLDTLHEQASALPQEHAESPDVRGRLSGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACELWIDEKE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with SPTBN1 polyclonal antibody (Cat # PAB20642) shows strong cytoplasmic and membranous positivity in cells in tubules and cells in glomeruli. -
Gene Info — SPTBN1
Entrez GeneID
6711Protein Accession#
Q01082Gene Name
SPTBN1
Gene Alias
ELF, SPTB2, betaSpII
Gene Description
spectrin, beta, non-erythrocytic 1
Omim ID
182790Gene Ontology
HyperlinkGene Summary
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
beta-G spectrin|beta-fodrin|beta-spectrin 2|beta-spectrin II|embryonic liver beta-fodrin
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Interactome
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Disease
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