ATP1B1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ATP1B1.
Immunogen
Recombinant protein corresponding to amino acids of human ATP1B1.
Sequence
SEFKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIVRFLEKYKDSAQRDDMIFEDCGDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDETYGYKEGKPCIIIKLNRVLGFKPKPPKNESLETYPVMKYNPN
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human colon with ATP1B1 polyclonal antibody (Cat # PAB20637) shows strong cytoplasmic and membranous positivity in glandular cells. -
Gene Info — ATP1B1
Entrez GeneID
481Protein Accession#
P05026Gene Name
ATP1B1
Gene Alias
ATP1B, MGC1798
Gene Description
ATPase, Na+/K+ transporting, beta 1 polypeptide
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
Beta 1-subunit of Na(+),K(+)-ATPase|Na+/K+ -ATPase beta 1 subunit|Na, K-ATPase beta-1 polypeptide|Na,K-ATPase beta 1 subunit|OTTHUMP00000032537|OTTHUMP00000032538|adenosinetriphosphatase|sodium/potassium-dependent ATPase beta-1 subunit|sodium/potassium-tr
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Interactome
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Pathway
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Disease
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