ANKK1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ANKK1.
Immunogen
Recombinant protein corresponding to amino acids of human ANKK1.
Sequence
EVNEDISQELMDSDSGNYLKRALQLSDRKNLVPRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQER
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with ANKK1 polyclonal antibody (Cat # PAB20626) shows cytoplasmic positivity in cells in seminiferus ducts and leydig cells. -
Gene Info — ANKK1
Entrez GeneID
255239Protein Accession#
Q8NFD2Gene Name
ANKK1
Gene Alias
PKK2
Gene Description
ankyrin repeat and kinase domain containing 1
Omim ID
608774Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq
Other Designations
X-kinase|protein kinase PKK2
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Interactome
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Disease
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