Immunohistochemical staining of human cerebral cortex with PAWR polyclonal antibody (Cat # PAB20610) shows strong cytoplasmic and nuclear positivity in neuronal cells and glial cells at 1:50-1:200 dilution.
Immunofluorescent staining of human cell line A-431 shows positivity in plasma membrane & cytoplasm. Using PAWR polyclonal antibody (Cat # PAB20610).
The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells. [provided by RefSeq
WT1-interacting protein,prostate apoptosis response protein 4,prostate apoptosis response protein PAR-4,transcriptional repressor PAR4