PARP14 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PARP14.
Immunogen
Recombinant protein corresponding to amino acids of human PARP14.
Sequence
AKEQESRADCISEFIEWQYNDNNTSHCFNKMTNLKLEDARREKKKTVDVKINHRHYTVNLNTYTATDTKGHSLSVQRLTKSKVDIPAHWSDMKQQNFCVVELLPSDPEYNTVASKFNQTCS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human colon with PARP14 polyclonal antibody (Cat # PAB20581) shows strong cytoplasmic and membranous positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with PARP14 polyclonal antibody (Cat # PAB20581) at 1-4 ug/mL dilution shows positivity in cytoplasm. -
Gene Info — PARP14
Entrez GeneID
54625Protein Accession#
Q460N5Gene Name
PARP14
Gene Alias
BAL2, KIAA1268
Gene Description
poly (ADP-ribose) polymerase family, member 14
Omim ID
610028Gene Ontology
HyperlinkGene Summary
Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent posttranslational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP14 belongs to the superfamily of enzymes that perform this modification (Ame et al., 2004 [PubMed 15273990]).[supplied by OMIM
Other Designations
B-aggressive lymphoma 2|collaborator of STAT6
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