SPINK5 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human esophagus with SPINK5 polyclonal antibody (Cat # PAB20549) shows strong cytoplasmic positivity in squamous epithelial cells (above basal layer) at 1:200-1:500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant SPINK5.
Immunogen
Recombinant protein corresponding to amino acids of human SPINK5.
Sequence
QQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPC
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human esophagus with SPINK5 polyclonal antibody (Cat # PAB20549) shows strong cytoplasmic positivity in squamous epithelial cells (above basal layer) at 1:200-1:500 dilution. -
Gene Info — SPINK5
Entrez GeneID
11005Protein Accession#
Q9NQ38Gene Name
SPINK5
Gene Alias
DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI
Gene Description
serine peptidase inhibitor, Kazal type 5
Gene Ontology
HyperlinkGene Summary
This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The inhibitor may play a role in skin and hair morphogenesis and anti-inflammatory and/or antimicrobial protection of mucous epithelia. Mutations may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
lymphoepithelial Kazal-type-related inhibitor|serine protease inhibitor, Kazal type 5
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Interactome
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Disease
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