Formalin-fixed and paraffin-embedded human hepatocarcinomareacted with DCLK1 polyclonal antibody (Cat # PAB2050), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Expression pattern of doublecortin and DCLK1 in normal mouse small intestine. A : Immunohistochemical staining of normal small intestine for DCLK1. Arrows indicate the cells positive for DCLK1 in the stem cell zone. B : Preincubation with blocking peptide completely abolished DCLK1 immunoreactivity. C : Immunohistochemical staining of normal small intestine for DCLK1. Brown indicates the cells positive for DCLK1 (indicated by the arrows).
DCAMKL1 is a microtubule-associated protein that phosphorylates itself and myelin basic protein (MBP; MIM 159430). DCAMKL1 has microtubule polymerizing activity that is independent of its protein kinase activity (Lin et al., 2000 [PubMed 11124993]).[supplied by OMIM
OTTHUMP00000018250,doublecortin and CaM kinase-like 1