GAB3 polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with GAB3 polyclonal antibody (Cat # PAB20494).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with GAB3 polyclonal antibody (Cat # PAB20494) shows moderate cytoplasmic positivity in hepatocytes.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant GAB3.
Immunogen
Recombinant protein corresponding to amino acids of human GAB3.
Sequence
CTLVPRRISLSGLDNMRTWKADVEGQSLRHRDKRLSLNLPCRFSPMYPTASASIEDSYVPMSPQAGASGLGPHCSPDDYIPMNSGSISSPLPELPANLEPPPVNRDLKPQRKSRPPPLDLRNLSIIREHASLTRTRTVPCSRTSF
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with GAB3 polyclonal antibody (Cat # PAB20494).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with GAB3 polyclonal antibody (Cat # PAB20494) shows moderate cytoplasmic positivity in hepatocytes. -
Gene Info — GAB3
Entrez GeneID
139716Protein Accession#
Q8WWW8Gene Name
GAB3
Gene Alias
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Gene Description
GRB2-associated binding protein 3
Omim ID
300482Gene Ontology
HyperlinkGene Summary
This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
DOS/Gab family member 3|Gab3 protein|Gab3 scaffolding protein|OTTHUMP00000026055
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Disease
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