OAZ1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant OAZ1.
Immunogen
Recombinant protein corresponding to amino acids of human OAZ1.
Sequence
QSRLTDAKRINWRTVLSGGSLYIEIPGGALPEGSKDSFAVLLEFAEEQLRADHVFICFHKNREDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMAYTFERESSGEEEE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human skeletal muscle with OAZ1 polyclonal antibody (Cat # PAB20480) shows strong cytoplasmic positivity in myocytes. -
Gene Info — OAZ1
Entrez GeneID
4946Protein Accession#
P54368Gene Name
OAZ1
Gene Alias
AZI, MGC138338, OAZ
Gene Description
ornithine decarboxylase antizyme 1
Omim ID
601579Gene Ontology
HyperlinkGene Summary
Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase and accelerates its degradation. [provided by RefSeq
Other Designations
antizyme 1
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Interactome
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Disease
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