EPS15 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant EPS15.
Immunogen
Recombinant protein corresponding to amino acids of human EPS15.
Sequence
CFFRQSTDPFATSSTDPFSAANNSSITSVETLKHNDPFAPGGTVVAASDSATDPFASVFGNESFGGGFADFSTLSKVNNEDPFRSATSSSVSNVVITKNVFEETSVKSEDEPPALPPKIGTPTRPCPLPPGKRSINKLDSPD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:10-1:20)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lymph node with EPS15 polyclonal antibody (Cat # PAB20429) shows strong cytoplasmic positivity in reaction center cells.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with EPS15 polyclonal antibody (Cat # PAB20429) at 1-4 ug/mL dilution shows positivity in cytoplasm, vesicles. -
Gene Info — EPS15
Entrez GeneID
2060Protein Accession#
P42566Gene Name
EPS15
Gene Alias
AF-1P, AF1P, MLLT5
Gene Description
epidermal growth factor receptor pathway substrate 15
Omim ID
600051Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
ALL1 fused gene from chromosome 1|OTTHUMP00000009896
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Interactome
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Pathway
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Disease
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