SEC23B polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with SEC23B polyclonal antibody (Cat # PAB20415) shows strong cytoplasmic positivity in exocrine glandular cells and moderate staining in Islet cells.
Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with SEC23B polyclonal antibody (Cat # PAB20415) at 1-4 ug/mL dilution shows positivity in vesicles.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant SEC23B.
Immunogen
Recombinant protein corresponding to amino acids of human SEC23B.
Sequence
MVQVHELSCEGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with SEC23B polyclonal antibody (Cat # PAB20415) shows strong cytoplasmic positivity in exocrine glandular cells and moderate staining in Islet cells.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with SEC23B polyclonal antibody (Cat # PAB20415) at 1-4 ug/mL dilution shows positivity in vesicles. -
Gene Info — SEC23B
Entrez GeneID
10483Protein Accession#
Q15437Gene Name
SEC23B
Gene Alias
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Gene Description
Sec23 homolog B (S. cerevisiae)
Omim ID
610512Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000042645|OTTHUMP00000042646|OTTHUMP00000042648|OTTHUMP00000063206|SEC23-like protein B|SEC23-related protein B|Sec23 homolog B|transport protein SEC23B
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Interactome
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Disease
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