CACNA2D1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human skeletal muscle with CACNA2D1 polyclonal antibody (Cat # PAB20413) shows strong cytoplasmic positivity in myocytes at 1:50-1:200 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant CACNA2D1.
Immunogen
Recombinant protein corresponding to amino acids of human CACNA2D1.
Sequence
QPKNPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEESGYTFIAPRDYCNDLKISDNNTEFL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human skeletal muscle with CACNA2D1 polyclonal antibody (Cat # PAB20413) shows strong cytoplasmic positivity in myocytes at 1:50-1:200 dilution. -
Gene Info — CACNA2D1
Entrez GeneID
781Protein Accession#
P54289Gene Name
CACNA2D1
Gene Alias
CACNA2, CACNL2A, CCHL2A, MHS3
Gene Description
calcium channel, voltage-dependent, alpha 2/delta subunit 1
Omim ID
114204Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
Other Designations
H_DJ0560O14.1|WUGSC:H_DJ0560O14.1|calcium channel, L type, alpha 2 polypeptide|dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit
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Interactome
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Pathway
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Disease
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