PSMA2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PSMA2.
Immunogen
Recombinant protein corresponding to amino acids of human PSMA2.
Sequence
SGAYFAWKATAMGKNYVNGKTFLEKRYNEDLELEDAIHTAILTLKESFEGQMTEDNIEVGICNEAGFRRLTPTEVKDYLAAIA
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of cell lysates with PSMA2 polyclonal antibody (Cat # PAB20412).
Lane 1 : NIH/3T3
Lane 2 : NBT-IIWestern Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with PSMA2 polyclonal antibody (Cat # PAB20412).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with PSMA2 polyclonal antibody (Cat # PAB20412) shows strong nuclear positivity in purkinje cells. -
Gene Info — PSMA2
Entrez GeneID
5683Protein Accession#
P25787Gene Name
PSMA2
Gene Alias
HC3, MU, PMSA2, PSC2
Gene Description
proteasome (prosome, macropain) subunit, alpha type, 2
Omim ID
176842Gene Ontology
HyperlinkGene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq
Other Designations
macropain subunit C3|multicatalytic endopeptidase complex subunit C3|proteasome alpha 2 subunit|proteasome component C3|proteasome subunit HC3
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