RNF43 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with RNF43 polyclonal antibody (Cat # PAB20409) shows strong nuclear positivity in cells in tubules.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant RNF43.
Immunogen
Recombinant protein corresponding to amino acids of human RNF43.
Sequence
CVDPWLHQHRTCPLCMFNITEGDSFSQSLGPSRSYQEPGRRLHLIRQHPGHAHYHLPAAYLLGPSRSAVARPPRPGPFLPSQEPGMGPRHHRFPRAAHPRAPGEQQRLAGAQHPYAQGWGLSHLQSTSQH
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with RNF43 polyclonal antibody (Cat # PAB20409) shows strong nuclear positivity in cells in tubules. -
Gene Info — RNF43
Entrez GeneID
54894Protein Accession#
Q68DV7Gene Name
RNF43
Gene Alias
DKFZp781H02126, DKFZp781H0392, FLJ20315, FLJ77466, FLJ99338, MGC125630, RNF124, URCC
Gene Description
ring finger protein 43
Gene Ontology
HyperlinkGene Summary
RNF43 is a HAP95 (AKAP8L; MIM 609475) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer (Yagyu et al., 2004 [PubMed 15492824]; Sugiura et al., 2008 [PubMed 18313049]).[supplied by OMIM
Other Designations
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Interactome
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Publication Reference
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Frequent frameshift mutations in 2 mononucleotide repeats of RNF43 gene and its regional heterogeneity in gastric and colorectal cancers.
Jo YS, Kim MS, Lee JH, Lee SH, An CH, Yoo NJ.
Human Pathology 2015 Nov; 46(11):1640.
Application：IHC, Human, Gastric cancer, Colorectal cancers.
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Frequent frameshift mutations in 2 mononucleotide repeats of RNF43 gene and its regional heterogeneity in gastric and colorectal cancers.
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