Immunohistochemical staining of human cerebellum with CALB2 polyclonal antibody (Cat # PAB20373) shows strong nuclear and cytoplasmic positivity in Purkinje cells and strong nuclear in cells in molecular layer at 1:50-1:200 dilution.
Immunofluorescent staining of human cell line A-431 with CALB2 polyclonal antibody (Cat # PAB20373) at 1-4 ug/mL dilution shows positivity in cytoplasm.
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. Three alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq