Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with CALB2 polyclonal antibody (Cat # PAB20372) at 1:250-1:500 dilution.
Immunohistochemical staining of human cerebellum with CALB2 polyclonal antibody (Cat # PAB20372) shows strong cytoplasmic and nuclear positivity in Purkinje cells and strong nuclear positivity in cells in molecular layer at 1:50-1:200 dilution.
Immunofluorescent staining of human cell line U-2 OS with CALB2 polyclonal antibody (Cat # PAB20372) at 1-4 ug/mL dilution shows positivity in cytoplasm.
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. Three alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq