PIM3 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
The PIM3 polyclonal antibody (Cat # PAB2037) is used in Western blot to detect PIM3 in mouse kidney tissue lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma reacted with PIM3 polyclonal antibody (Cat # PAB2037) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PIM3.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PIM3.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
The PIM3 polyclonal antibody (Cat # PAB2037) is used in Western blot to detect PIM3 in mouse kidney tissue lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma reacted with PIM3 polyclonal antibody (Cat # PAB2037) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. -
Gene Info — PIM3
Entrez GeneID
415116Protein Accession#
NP_001001852;Q86V86Gene Name
PIM3
Gene Alias
pim-3
Gene Description
pim-3 oncogene
Omim ID
610580Gene Ontology
HyperlinkGene Summary
PIM3 belongs to a family of protooncogenes that encode serine/threonine protein kinases (Mikkers et al., 2004 [PubMed 15199164]).[supplied by OMIM
Other Designations
serine/threonine kinase Pim-3|serine/threonine-protein kinase pim-3
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Publication Reference
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Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors.
Mikkers H, Nawijn M, Allen J, Brouwers C, Verhoeven E, Jonkers J, Berns A.
Molecular and Cellular Biochemistry 2004 Jul; 24(13):6104.
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Developmental expression of pim kinases suggests functions also outside of the hematopoietic system.
Eichmann A, Yuan L, Breant C, Alitalo K, Koskinen PJ.
Oncogene 2000 Feb; 19(9):1215.
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Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors.
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