TAF5 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant TAF5.
Immunogen
Recombinant protein corresponding to amino acids of human TAF5.
Sequence
TVVSGSASGPAAPGKVGSVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDF
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:10-1:20)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lymph node with TAF5 polyclonal antibody (Cat # PAB20341) shows strong nuclear positivity in reaction center cells and lymphoid cells outside reaction center.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with TAF5 polyclonal antibody (Cat # PAB20341) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli, vesicles. -
Gene Info — TAF5
Entrez GeneID
6877Protein Accession#
Q15542Gene Name
TAF5
Gene Alias
TAF2D, TAFII100
Gene Description
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
Omim ID
601787Gene Ontology
HyperlinkGene Summary
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex. This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex. [provided by RefSeq
Other Designations
OTTHUMP00000020402|TATA box binding protein (TBP)-associated factor 2D|TATA box binding protein (TBP)-associated factor, RNA polymerase II, D, 100kD|TBP-associated factor 5|transcription initiation factor TFIID 100 kD subunit
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Interactome
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Pathway
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