SEC16A polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with SEC16A polyclonal antibody (Cat # PAB20311) shows cytoplasmic positivity with a granular pattern in exocrine glandular cells at 1:20-1:50 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant SEC16A.
Immunogen
Recombinant protein corresponding to amino acids of human SEC16A.
Sequence
PLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKAPGDLPAAGGPPSGAMPFYNPAQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with SEC16A polyclonal antibody (Cat # PAB20311) shows cytoplasmic positivity with a granular pattern in exocrine glandular cells at 1:20-1:50 dilution. -
Gene Info — SEC16A
Entrez GeneID
9919Protein Accession#
O15027Gene Name
SEC16A
Gene Alias
FLJ26737, KIAA0310, RP11-413M3.10, SEC16L, p250
Gene Description
SEC16 homolog A (S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
The selective export of proteins and lipids from the endoplasmic reticulum (ER) is mediated by the coat protein complex II (COPII) that assembles at discrete sites on the membrane known as endoplasmic reticulum exit sites (ERES), or transitional ER sites. SEC16A is a peripheral membrane protein that defines ERES in mammalian cells and is required for protein transport from ER to Golgi (Watson et al., 2006 [PubMed 17005010]).
Other Designations
SEC16 homolog A
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