SEC31A polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebral cortex with SEC31A polyclonal antibody (Cat # PAB20295) shows strong cytoplasmic and nuclear(nucleolar) positivity in neuronal cells.
Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with SEC31A polyclonal antibody (Cat # PAB20295) at 1-4 ug/mL dilution shows positivity in cytoplasm, vesicles.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant SEC31A.
Immunogen
Recombinant protein corresponding to amino acids of human SEC31A.
Sequence
NWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebral cortex with SEC31A polyclonal antibody (Cat # PAB20295) shows strong cytoplasmic and nuclear(nucleolar) positivity in neuronal cells.Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with SEC31A polyclonal antibody (Cat # PAB20295) at 1-4 ug/mL dilution shows positivity in cytoplasm, vesicles. -
Gene Info — SEC31A
Entrez GeneID
22872Protein Accession#
O94979Gene Name
SEC31A
Gene Alias
ABP125, ABP130, DKFZp686N07171, HSPC275, HSPC334, KIAA0905, MGC90305, SEC31L1
Gene Description
SEC31 homolog A (S. cerevisiae)
Omim ID
610257Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000160810|SEC31 homolog A|SEC31-like 1|protein-transport protein SEC31|yeast Sec31p homolog
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Interactome
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Disease
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