SCAP polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant SCAP.
Immunogen
Recombinant protein corresponding to amino acids of human SCAP.
Sequence
EVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLED
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:10-1:20)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human stomach with SCAP polyclonal antibody (Cat # PAB20276) shows strong cytoplasmic positivity in glandular cells at 1:10-1:20 dilution. -
Gene Info — SCAP
Entrez GeneID
22937Protein Accession#
Q12770Gene Name
SCAP
Gene Alias
KIAA0199
Gene Description
SREBF chaperone
Omim ID
601510Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. [provided by RefSeq
Other Designations
SREBF chaperone protein|SREBP cleavage activating protein|SREBP cleavage-activating protein|sterol regulatory element binding protein cleavage-activating protein
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Interactome
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Disease
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