SCAP polyclonal antibody

Catalog # PAB20276

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Price

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Quantity

Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human stomach with SCAP polyclonal antibody (Cat # PAB20276) shows strong cytoplasmic positivity in glandular cells at 1:10-1:20 dilution.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against recombinant SCAP.

    Immunogen

    Recombinant protein corresponding to amino acids of human SCAP.

    Sequence

    EVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLED

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunohistochemistry (1:10-1:20)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining of human stomach with SCAP polyclonal antibody (Cat # PAB20276) shows strong cytoplasmic positivity in glandular cells at 1:10-1:20 dilution.
  • Gene Info — SCAP

    Entrez GeneID

    22937

    Protein Accession#

    Q12770

    Gene Name

    SCAP

    Gene Alias

    KIAA0199

    Gene Description

    SREBF chaperone

    Omim ID

    601510

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. [provided by RefSeq

    Other Designations

    SREBF chaperone protein|SREBP cleavage activating protein|SREBP cleavage-activating protein|sterol regulatory element binding protein cleavage-activating protein

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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