DDX10 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with DDX10 polyclonal antibody (Cat # PAB20272) shows strong cytoplasmic positivity in cells of seminiferus ducts.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant DDX10.
Immunogen
Recombinant protein corresponding to amino acids of human DDX10.
Sequence
KVPVKEIKINPEKLIDVQKKLESILAQDQDLKERAQRCFVSYVRSVYLMKDKEVFDVSKLPIPEYALSLGLAVAPRVRFLQKMQKQPTKELVRSQADKVIEPRAPSLTNDEVEEFRAYFNEKMSILQKGGKRLEGTEHRQDNDTGNEE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with DDX10 polyclonal antibody (Cat # PAB20272) shows strong cytoplasmic positivity in cells of seminiferus ducts. -
Gene Info — DDX10
Entrez GeneID
1662Protein Accession#
Q13206Gene Name
DDX10
Gene Alias
HRH-J8
Gene Description
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
Omim ID
601235Gene Ontology
HyperlinkGene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies. [provided by RefSeq
Other Designations
DDX10-NUP98 fusion protein type 2|DEAD box-10|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 10 (RNA helicase)
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Interactome
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Disease
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