ARPC1A polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ARPC1A.
Immunogen
Recombinant protein corresponding to amino acids of human ARPC1A.
Sequence
HGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLKTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDIPKQSIQRNMSAMERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGI
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:10-1:20)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with ARPC1A polyclonal antibody (Cat # PAB20270) at 1:250-1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human stomach with ARPC1A polyclonal antibody (Cat # PAB20270) shows strong cytoplasmic and membranous positivity in glandular cells at 1:10-1:20 dilution. -
Gene Info — ARPC1A
Entrez GeneID
10552Protein Accession#
Q92747Gene Name
ARPC1A
Gene Alias
Arc40, SOP2Hs, SOP2L
Gene Description
actin related protein 2/3 complex, subunit 1A, 41kDa
Omim ID
604220Gene Ontology
HyperlinkGene Summary
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. [provided by RefSeq
Other Designations
SOP2-like protein|actin binding protein (Schizosaccharomyces pombe sop2-like)|actin related protein 2/3 complex subunit 1A
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Interactome
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Pathway
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Disease
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