Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with ROBLD3 polyclonal antibody (Cat # PAB20265) at 1:250-1:500 dilution.
The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
MAPKSP1 adaptor protein,OTTHUMP00000018850,endosomal adaptor protein,mitogen activated protein binding protein interacting protein,mitogen-activated protein-binding protein-interacting protein,mitogen-activated protein-binding protein-interacting protein