NPAS3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant NPAS3.
Immunogen
Recombinant protein corresponding to amino acids of human NPAS3.
Sequence
SQVELTGSSVFDYVHPGDHVEMAEQLGMKLPPGRGLLSQGTAEDGASSASSSSQSETPEPVESTSPSLLTTDNTLERSFFIRMKSTLTKRGVHIKSSGYKV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with NPAS3 polyclonal antibody (Cat # PAB20136) shows moderate cytoplasmic and nuclear positivity in purkinje cells.Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with NPAS3 polyclonal antibody (Cat # PAB20136) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli. -
Gene Info — NPAS3
Entrez GeneID
64067Protein Accession#
Q8IXF0Gene Name
NPAS3
Gene Alias
MOP6, PASD6, bHLHe12
Gene Description
neuronal PAS domain protein 3
Omim ID
609430Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and mental retardation. Alternate splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000178811|basic-helix-loop-helix-PAS protein
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Interactome
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Disease
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