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Last updated: 2016/10/23
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SSRP1 polyclonal antibody

  • Catalog # : PAB20128
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against recombinant SSRP1.
  • Immunogen:
  • Recombinant protein corresponding to amino acids of human SSRP1.
  • Sequence:
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (1:50-1:200)
    Immunofluorescence (1-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human testis with SSRP1 polyclonal antibody (Cat # PAB20128) shows strong nuclear positivity in cells of seminiferus ducts at 1:50-1:200 dilution.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of human cell line A-431 with SSRP1 polyclonal antibody (Cat # PAB20128) at 1-4 ug/mL dilution shows positivity in nucleus, cytoplasm.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6749
  • Gene Name:
  • SSRP1
  • Gene Alias:
  • FACT,FACT80,T160
  • Gene Description:
  • structure specific recognition protein 1
  • Gene Summary:
  • The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq
  • Other Designations:
  • chromatin-specific transcription elongation factor 80 kDa subunit,cisplatin-DNA SSRP,facilitates chromatin remodeling 80 kDa subunit,high mobility group box,recombination signal sequence recognition protein
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