PREX1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human hippocampus with PREX1 polyclonal antibody (Cat # PAB20101) shows moderate cytoplasmic positivity in neuronal cells.
Immunofluorescence
Immunofluorescent staining of human cell line A-431 with PREX1 polyclonal antibody (Cat # PAB20101) at 1-4 ug/mL dilution shows positivity in cytoplasm, vesicles.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PREX1.
Immunogen
Recombinant protein corresponding to amino acids of human PREX1.
Sequence
CAGQCILKVNGSNVMNDGAPEVLEHFQAFRSRREEALGLYQWIYHTHEDAQEARASQEASTEDPSGEQAQEEDQADSAFPLLSLGPRLSLCEDSPMVTLTVDNVHLEHGVVYEYVSTAGVRCHVLEKIVEP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human hippocampus with PREX1 polyclonal antibody (Cat # PAB20101) shows moderate cytoplasmic positivity in neuronal cells.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with PREX1 polyclonal antibody (Cat # PAB20101) at 1-4 ug/mL dilution shows positivity in cytoplasm, vesicles. -
Gene Info — PREX1
Entrez GeneID
57580Protein Accession#
Q8TCU6Gene Name
PREX1
Gene Alias
KIAA1415, P-REX1
Gene Description
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Omim ID
606905Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq
Other Designations
OTTHUMP00000031228|phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1
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Interactome
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Pathway
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Disease
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