Western blot analysis of FXN polyclonal antibody (Cat # PAB2010) in 293 cell line lysates (35 ug/lane). FXN (arrow) was detected using the purified Polyclonal antibody.
Western Blot (Transfected lysate)
Western blot analysis of FXN (arrow) using FXN polyclonal antibody (Cat # PAB2010). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FXN gene (Lane 2) (Origene Technologies).
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with FXN polyclonal antibody (Cat # PAB2010) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq