TJP1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant TJP1.
Immunogen
Recombinant protein corresponding to amino acids of human TJP1.
Sequence
ASSQPAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDERATLLNVPDLSDSIHSANASERDDISEIQSLASDHSGR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with TJP1 polyclonal antibody (Cat # PAB20077) shows distinct membranous and cytoplasmic positivity in cells of glomeruli.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with TJP1 polyclonal antibody (Cat # PAB20077) at 1-4 ug/mL dilution shows positivity in plasma membrane, cytoplasm, cell junctions. -
Gene Info — TJP1
Entrez GeneID
7082Protein Accession#
Q07157Gene Name
TJP1
Gene Alias
DKFZp686M05161, MGC133289, ZO-1
Gene Description
tight junction protein 1 (zona occludens 1)
Omim ID
601009Gene Ontology
HyperlinkGene Summary
This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000174520|tight junction protein 1|tight junction protein ZO-1|zona occludens 1|zonula occludens 1 protein
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Interactome
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