RPGR polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with RPGR polyclonal antibody (Cat # PAB20072) shows distinct cytoplasmic and membranous positivity in hepatocytes at 1:200-1:500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant RPGR.
Immunogen
Recombinant protein corresponding to amino acids of human RPGR.
Sequence
EINDTCLSVATFLPYSSLTSGNVLQRTLSARMRRRERERSPDSFSMRRTLPPIEGTLGLSACFLPNSVFPRCSERNLQESVLSEQDLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTHIMSLN
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with RPGR polyclonal antibody (Cat # PAB20072) shows distinct cytoplasmic and membranous positivity in hepatocytes at 1:200-1:500 dilution. -
Gene Info — RPGR
Entrez GeneID
6103Protein Accession#
Q92834Gene Name
RPGR
Gene Alias
COD1, CORDX1, CRD, PCDX, RP15, RP3, XLRP3, orf15
Gene Description
retinitis pigmentosa GTPase regulator
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined. [provided by RefSeq
Other Designations
OTTHUMP00000023140|retinitis pigmentosa 15, cone dystrophy 1 (X-linked)|retinitis pigmentosa 3 GTPase regulator
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Interactome
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Disease
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