MYO5A polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant MYO5A.
Immunogen
Recombinant protein corresponding to amino acids of human MYO5A.
Sequence
QNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGVAVNLIPG
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with MYO5A polyclonal antibody (Cat # PAB20053) shows strong cytoplasmic positivity in purkinje cells. -
Gene Info — MYO5A
Entrez GeneID
4644Protein Accession#
Q9Y4I1Gene Name
MYO5A
Gene Alias
GS1, MYH12, MYO5, MYR12
Gene Description
myosin VA (heavy chain 12, myoxin)
Gene Ontology
HyperlinkGene Summary
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000174452|dilute|myosin V|myosin VA|myosin heavy chain 12|myosin, heavy polypeptide kinase|myoxin
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Interactome
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Disease
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