FAM12B polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human epididymis with FAM12B polyclonal antibody (Cat # PAB20050) shows membranous positivity in glandular cells at 1:50-1:200 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant FAM12B.
Immunogen
Recombinant protein corresponding to amino acids of human FAM12B.
Sequence
EVSWREFMKQHYLSPSREFREYKCDVLMRENEALKDKSSHMFIYISWYKIEHICTSDNWMDRFRNAYVWVQNPLKVLKCHQENSKNSYTESRSFNYIEFHCSMDGYVDSIEDLKMVEPIGN
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human epididymis with FAM12B polyclonal antibody (Cat # PAB20050) shows membranous positivity in glandular cells at 1:50-1:200 dilution. -
Gene Info — FAM12B
Entrez GeneID
64184Protein Accession#
P56851Gene Name
FAM12B
Gene Alias
EP3B, HE3-BETA, HE3B
Gene Description
family with sequence similarity 12, member B (epididymal)
Omim ID
611582Gene Ontology
HyperlinkGene Summary
Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells. [provided by RefSeq
Other Designations
OTTHUMP00000028281|epididymal secretory protein E3 beta|human epididymis-specific 3 beta
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