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CTCF polyclonal antibody

  • Catalog # : PAB19945
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CTCF.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human CTCF.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 82.8, 150
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody reacts with endogenous CTCF protein. A BLAST analysis was used to suggest reactivity with CTCF from human, mouse, horse, bovine, panda, rabbit, Danio, and chicken based on a 100% homology with the immunizing sequence. Cross-reactivity with CTCF from other sources has not been determined.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity purification
  • Recommend Usage:
  • ELISA (1:200000-1:250000)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of H929 nuclear cell with CTCF polyclonal antibody (Cat # PAB19945) at 1.2 ug/mL dilution.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • CTCF
  • Gene Alias:
  • -
  • Gene Description:
  • CCCTC-binding factor (zinc finger protein)
  • Gene Summary:
  • This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. [provided by RefSeq
  • Other Designations:
  • 11 zinc finger transcriptional repressor,11-zinc finger protein,CCCTC-binding factor,CTCFL paralog,transcriptional repressor CTCF
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