AICDA polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of AICDA.
Immunogen
A synthetic peptide corresponding to 16 amino acids near N-terminus of human AICDA.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Peptide affinity purification
Recommend Usage
ELISA (1:1000-1:10000)
Western Blot (1:200-1000)
Immunohistochemistry (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In serum (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of human placenta (Lane 1) and human liver (Lane 2) tissue lysate with AICDA polyclonal antibody (Cat # PAB19827) at 1:200 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed paraffin-embedded human lymph node showing staining with AICDA polyclonal antibody (Cat # PAB19827) at 1:100 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — AICDA
Entrez GeneID
57379Protein Accession#
Q9GZX7Gene Name
AICDA
Gene Alias
AID, ARP2, CDA2, HIGM2
Gene Description
activation-induced cytidine deaminase
Gene Ontology
HyperlinkGene Summary
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq
Other Designations
activation-induced deaminase|integrated into Burkitt's lymphoma cell line Ramos
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Interactomes
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Pathways
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Diseases
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