AIFM2 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of AIFM2.
Immunogen
A synthetic peptide corresponding to 13 amino acids at N-terminus of human AIFM2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
ELISA (1:80000)
Western Blot (1:200-1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In serum (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of human fetal liver tissue lysate with AIFM2 polyclonal antibody (Cat # PAB19822) at 1:1000 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — AIFM2
Entrez GeneID
84883Protein Accession#
Q9BRQ8Gene Name
AIFM2
Gene Alias
AMID, PRG3, RP11-367H5.2
Gene Description
apoptosis-inducing factor, mitochondrion-associated, 2
Omim ID
605159Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has significant homology to NADH oxidoreductases and the apoptosis-inducing factor PDCD8/AIF. Overexpression of this gene has been shown to induce apoptosis. The expression of this gene is found to be induced by tumor suppressor protein p53 in colon caner cells. [provided by RefSeq
Other Designations
5430437E11Rik|OTTHUMP00000019739|OTTHUMP00000019740|apoptosis-inducing factor (AIF)-homologous mitochondrion-associated inducer of death|apoptosis-inducing factor (AIF)-like mitchondrion-associated inducer of death|apoptosis-inducing factor (AIF)-like mit
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Interactome
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Disease
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Publication Reference
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Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
Peiyu Liang, Xinyi Zhang, Yahui Zhang, Yifan Wu, Yinghao Song, Xueyang Wang, Taoxiang Chen, Wanhong Liu, Biwen Peng, Jun Yin, Fanggang He, Yuanteng Fan, Song Han, Xiaohua He.
Free Radical Biology & Medicine 2023 Feb; 195:329.
Application:WB-Ce, WB-Ti, Mouse , Mouse brain, N2a cells .
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Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
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