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Last updated: 2016/12/4
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ZYX polyclonal antibody

  • Catalog # : PAB19818
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ZYX.
  • Immunogen:
  • A synthetic peptide corresponding to 15 amino acids near internal region of human ZYX.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (1:500-1000)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HeLa cell lysate with ZYX polyclonal antibody (Cat # PAB19818) at 1:1000 dilution.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of HeLa with ZYX polyclonal antibody (Cat # PAB19818) at 1:50 dilution.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7791
  • Gene Name:
  • ZYX
  • Gene Alias:
  • ESP-2,HED-2
  • Gene Description:
  • zyxin
  • Gene Summary:
  • Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq
  • Other Designations:
  • -
  • Gene Pathway
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