ANXA6 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ANXA6.
Immunogen
A synthetic peptide corresponding to 16 amino acids at N-terminus of human ANXA6.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Peptide affinity purification
Recommend Usage
ELISA (1:20000-1:80000)
Western Blot (1:200-1000)
Immunohistochemistry (1:50-200)
The optimal working dilution should be determined by the end user.Storage Buffer
In serum (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of 293 (Lane 1), human fetal liver (Lane 2) and HepG2 (Lane 3) lysate with ANXA6 polyclonal antibody (Cat # PAB19793) at 1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed paraffin-embedded human fetal liver showing staining with ANXA6 polyclonal antibody (Cat # PAB19793) at 1:100 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ANXA6
Entrez GeneID
309Protein Accession#
P08133Gene Name
ANXA6
Gene Alias
ANX6, CBP68
Gene Description
annexin A6
Omim ID
114070Gene Ontology
HyperlinkGene Summary
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. [provided by RefSeq
Other Designations
annexin VI|annexin VI (p68)|calcium-binding protein p68|calelectrin|calphobindin II
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Interactome
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Disease
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