LRP5 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
LRP5 polyclonal antibody (Cat # PAB1979) is used in Western blot to detect recombinant human LRP5 (Lane 1) and mouse LRP5 (Lane 2) proteins in transfected 293 cell lysates. Data is kindly provided by Drs. V. Harris and S. Aaronson from the Mount Sinai School of Medicine (New York, NY) .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with LRP5 polyclonal antibody (Cat # PAB1979), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of LRP5.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human LRP5.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
LRP5 polyclonal antibody (Cat # PAB1979) is used in Western blot to detect recombinant human LRP5 (Lane 1) and mouse LRP5 (Lane 2) proteins in transfected 293 cell lysates. Data is kindly provided by Drs. V. Harris and S. Aaronson from the Mount Sinai School of Medicine (New York, NY) .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with LRP5 polyclonal antibody (Cat # PAB1979), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. -
Gene Info — LRP5
Entrez GeneID
4041Protein Accession#
NP_002326;Q9UP66Gene Name
LRP5
Gene Alias
BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2
Gene Description
low density lipoprotein receptor-related protein 5
Gene Ontology
HyperlinkOther Designations
exudative vitreoretinopathy 1|low density lipoprotein receptor-related protein 7|osteoporosis pseudoglioma syndrome
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Interactome
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Pathway
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Disease
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Publication Reference
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Diverse role of LDL receptor-related protein in the clearance of proteases and in signaling.
Strickland DK, Ranganathan S.
Journal of Thrombosis and Haemostasis 2003 Jul; 1(7):1663.
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LDL receptor-related proteins in neurodevelopment.
May P, Herz J.
Traffic (Copenhagen, Denmark) 2003 May; 4(5):291.
Application：Flow Cyt, IF, Human, Mammalian cells.
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Soluble low-density lipoprotein receptor-related protein.
Grimsley PG, Quinn KA, Owensby DA.
Trends in Cardiovascular Medicine 1998 Nov; 8(8):363.
Application：ELISA, WB, Human, Human plasma, Human serum.
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Diverse role of LDL receptor-related protein in the clearance of proteases and in signaling.
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