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CLDN1 polyclonal antibody

  • Catalog # : PAB19765
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against full length recombinant CLDN1.
  • Immunogen:
  • Recombinant protein corresponding to full length human CLDN1.
  • Sequence:
  • MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 22.7
  • Reactivity:
  • Human
  • Specificity:
  • It displayed on membrane surface of lipoparticles.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In unpurified whole serum
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of HEK293 cells over-expressing SLC2A1 (Lane 1) or a nono-specific control receptor (Lane 2) using CLDN1 polyclonal antibody (Cat # PAB19765) at 1:200 dilution.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 9076
  • Gene Name:
  • CLDN1
  • Gene Alias:
  • CLD1,ILVASC,SEMP1
  • Gene Description:
  • claudin 1
  • Gene Summary:
  • Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq
  • Other Designations:
  • senescence-associated epithelial membrane protein 1
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