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Last updated: 2017/4/23

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TPH2 polyclonal antibody

  • Catalog # : PAB19755
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of TPH2.
  • Immunogen:
  • A synthetic peptide correspoding to amino acids 16-29 at N-terminus ofhuman TPH2.
  • Sequence:
  • RGFSLDSAVPEEHQC
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 56.1
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:128000)
    Western Blot (0.5-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • TPH2 polyclonal antibody (Cat # PAB19755) (0.5 ug/mL) staining of HEK293 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • TPH2
  • Gene Alias:
  • FLJ37295,MGC138871,MGC138872,NTPH
  • Gene Description:
  • tryptophan hydroxylase 2
  • Gene Summary:
  • This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq
  • Other Designations:
  • neuronal tryptophan hydroxylase,tryptophan 5-monooxygenase 2
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