Product Browser

Last updated: 2016/12/4

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

AIRE polyclonal antibody

  • Catalog # : PAB19745
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of AIRE.
  • Immunogen:
  • A synthetic peptide corresponding to 15 amino acids at C-terminus of human AIRE.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Recommend Usage:
  • ELISA (1:80000)
    Western Blot (1:200-500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 1.
  • PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator–dependent autoimmunity.
    Mathieu AL, Verronese E, Rice GI, Fouyssac F, Bertrand Y, Picard C, Chansel M, Walter JE, Notarangelo LD, Butte MJ, Nadeau KC, Csomos K, Chen DJ, Chen K, Delgado A, Rigal C, Bardin C, Schuetz C, Moshous D, Reumaux H, Plenat F, Phan A, Zabot MT, Balme B, Viel S, Bienvenu J, Cochat P, van der Burg M, Caux C, Kemp EH, Rouvet I, Malcus C, Meritet JF, Lim A, Crow YJ, Fabien N, Menetrier-Caux C, De Villartay JP, Walzer T, Belot A.J Allergy Clin Immunol. 2015 Apr 1.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of human thymus (Lane 1) and human testis (Lane 2) tissue lysate with AIRE polyclonal antibody (Cat # PAB19745) at 1:500 dilution.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 326
  • Gene Name:
  • AIRE
  • Gene Alias:
  • AIRE1,APECED,APS1,APSI,PGA1
  • Gene Description:
  • autoimmune regulator
  • Gene Summary:
  • This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). [provided by RefSeq
  • Other Designations:
  • autoimmune polyendocrinopathy candidiasis ectodermal dystrophy
  • RSS
  • YouTube
  • Linkedin
  • Facebook