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ADAM15 polyclonal antibody

  • Catalog # : PAB19739
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ADAM15.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human ADAM15.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Recommend Usage:
  • ELISA (1:80000)
    Western Blot (1:200-1000)
    Immunohistochemistry (1:100-500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (2% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of human fetal liver tissue lysate with ADAM15 polyclonal antibody (Cat # PAB19739) at 1:200 dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of formalin-fixed paraffin-embedded human stomach showing membrane staining with ADAM15 polyclonal antibody (Cat # PAB19739) at 1:100 dilution.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8751
  • Gene Name:
  • ADAM15
  • Gene Alias:
  • MDC15
  • Gene Description:
  • ADAM metallopeptidase domain 15
  • Gene Summary:
  • The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000015780,a disintegrin and metalloproteinase domain 15,a disintegrin and metalloproteinase domain 15 (metargidin),metalloprotease RGD disintegrin protein,metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15,metargidin
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