Products

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human kidney with HOXD10 polyclonal antibody (Cat # PAB19703) (3.8 ug/mL). Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Enzyme-linked Immunoabsorbent Assay

Flow Cytometry

HOXD10 polyclonal antibody (Cat # PAB19703) Flow cytometric analysis of paraformaldehyde fixed HEK293 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Entrez GeneID

3236

Protein Accession#

NP_002139.2

Gene Name

HOXD10

Gene Alias

HOX4, HOX4D, HOX4E, Hox-4.4

Gene Description

homeobox D10

Omim ID

142984 192950

Gene Ontology

Hyperlink

Gene Summary

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq

Other Designations

homeo box 4D|homeo box D10