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SLC46A1 polyclonal antibody

  • Catalog # : PAB19698
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of SLC46A1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 233-247 at internal region of human SLC46A1.
  • Sequence:
  • C-LKEPKSTRLFTFRH
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 49.8
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • Western Blot (0.3-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • SLC46A1 polyclonal antibody (Cat # PAB19698) (0.3 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • SLC46A1
  • Gene Alias:
  • HCP1,MGC9564,PCFT
  • Gene Description:
  • solute carrier family 46 (folate transporter), member 1
  • Gene Summary:
  • This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a transmembrane heme transporter in duodenal enterocytes and, potentially, in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene cause the autosomal recessive hereditary folate malabsorption (HFM) disease. HFM is characterized by folate deficiency due to reduced intestinal folate absorption and subsequent anemia, hypoimmunoglobulinemia, and recurrent infections. [provided by RefSeq
  • Other Designations:
  • heme carrier protein 1,proton-coupled folate transporter,solute carrier family 46, member 1
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